Nitrofurantion may be less effective at treating urinary tract infections if it's taken with probenecid or sulfinpyrazone, because these medicines stop as much nitrofurantion getting into the urine. If you need to take an antacid you should take it at least two hours before or two hours after taking a nitrofurantoin dose. Antacids that contain magnesium salts such as magnesium trisilicate may reduce the absorption of nitrofurantion from the gut, which could make it less effective at treating your infection. You shouldn't take an antacid medicine (remedies for indigestion and heartburn) at the same time of day as nitrofurantoin. Drinking lots of water will help dilute your urine and make it less painful to go to the toilet. These can make the antibiotic less effective at treating the urine infection. It's fine to take over-the-counter painkillers like paracetamol or ibuprofen while you're taking nitrofurantoin.ĭon't take cystitis remedies (like potassium citrate or sodium citrate) to relieve the symptoms of your UTI while you're taking nitrofurantoin. Similarly, check with your doctor or pharmacist before taking any new medicines while taking nitrofurantoin, to make sure that the combination is safe. It's important to tell your doctor or pharmacist if you're already taking any medicines, including those bought without a prescription and herbal medicines, before you start a course of nitrofurantoin.
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